Juvenile xanthogranuloma - Talavou Xanthogranuloma
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ReferencesJuvenile xanthogranuloma (JXG) ose tulaga masani ma o le ituaiga masani o non‑Langerhans cell histiocytic disorder i tamaiti. I le tusa ma le 75 % o faʻamaʻi, o nei manuʻa (lesions) e faʻaalia i totonu o le tausaga muamua o le olaga, ma sili atu i le 15‑20 % o tagata gasegase e maua mai i le fanau mai. E ui e seasea i tagata matutua, o le JXG e masani lava ona tupu i tagata i le tuai o le luasefulu i le tolusefulu, ma o le tele o tagata matutua e naʻo le tasi le manuʻa (lesion). I le falemaʻi, e foliga mai e tasi pe tele tuʻu lanu samasama‑lanu‑lanu enaena poʻo tuʻi, e masani lava i luga o le foliga, ua, ma le tino pito i luga. O manuʻa o le gutu (oral lesions) e le masani ai ae e ono foliga mai e pei o se paʻu samasama i itu o le laulaufaiva poʻo se isi mea i le gutu, atonu e oʻo atu ai i le papala ma le toto. O manuʻa o le paʻu (cutaneous lesions) e masani lava e le mafua ai ni faʻailoga ma e masani ona alu ese naʻo latou i le tele o tausaga. E ui ina seasea, o le a’afiaga o mata (eye involvement) o le fa’afitauli sili lea ona taatele i tua atu o le paʻu, sosoo ai ma le aafia o le mama. Ocular JXG e masani ona a’afia ai na’o le tasi le mata ma e tupu i le itiiti ifo i le 0.5 % o tagata mama’i, e ui e tusa ma le 40 % oi latou e a’afia i le mata e tele fo’i manuʻa (lesions) paʻu pe a maua.
Juvenile xanthogranuloma (JXG) is a relatively common entity and is the most common form of non-Langerhans cell histiocytic disorder of childhood., It is estimated that in 75% of cases, lesions appear during the first year of life, with >15-20% of patients having lesions at birth. JXG is rare in adults, with a peak incidence in the late twenties to thirties. The majority of adult patients have solitary lesions. Typically, the clinical presentation consists of solitary or multiple yellow-orange-brown firm papules or nodules. The most common locations are the face, neck, and upper torso. Oral lesions are rare and often occur as a yellow nodule on the lateral aspects of the tongue. Oral lesions can also arise on the gingival, buccal mucosa, and midline hard palate and may ulcerate and bleed. Cutaneous lesions are usually asymptomatic, and most lesions spontaneously involute over the course of several years. Although occurring rarely, ocular involvement is the most common extracutaneous site involved, followed by the lungs. Ocular JXG is nearly always unilateral and develops in less than 0.5% of patients. Approximately 40% of patients with ocular JXG, however, have multiple cutaneous lesions at the time of diagnosis.
Juvenile xanthogranuloma (JXG) is a relatively common entity and is the most common form of non-Langerhans cell histiocytic disorder of childhood., It is estimated that in 75% of cases, lesions appear during the first year of life, with >15-20% of patients having lesions at birth. JXG is rare in adults, with a peak incidence in the late twenties to thirties. The majority of adult patients have solitary lesions. Typically, the clinical presentation consists of solitary or multiple yellow-orange-brown firm papules or nodules. The most common locations are the face, neck, and upper torso. Oral lesions are rare and often occur as a yellow nodule on the lateral aspects of the tongue. Oral lesions can also arise on the gingival, buccal mucosa, and midline hard palate and may ulcerate and bleed. Cutaneous lesions are usually asymptomatic, and most lesions spontaneously involute over the course of several years. Although occurring rarely, ocular involvement is the most common extracutaneous site involved, followed by the lungs. Ocular JXG is nearly always unilateral and develops in less than 0.5% of patients. Approximately 40% of patients with ocular JXG, however, have multiple cutaneous lesions at the time of diagnosis.
Juvenile xanthogranuloma (JXG) o le fa'ama'i e le masani ai, fa'ama'i mama o se vaega o le tele o non‑Langerhans cell histiocytoses. E masani ona fa'aalia e pei o se tasi po'o le sili atu fo'i tu'u mumu po'o samasama, e masani ona maua i le ulu po'o le ua. Ole tele o le JXG e tupu i le fanau mai po'o le tausaga muamua o le olaga. E ui e le masani ai, o nisi taimi e mafai ona afaina vaega i tua atu o le paʻu, ma le aʻafia o mata. E masani lava, o le JXG i luga o le paʻu e alu ese na o latou ma e masani lava e le manaʻomia togafitiga.
Juvenile xanthogranulomas (JXGs) are uncommon, benign diseases that are part of a larger category of non-Langerhans cell histiocytoses. They typically show up as one or more red or yellowish lumps, often found on the head or neck. Most JXGs develop either at birth or within the first year of life. While it's unusual, sometimes they can affect areas beyond the skin, with eye involvement being something to watch for according to existing literature. Generally, JXGs on the skin go away on their own and typically don't need treatment.
Juvenile xanthogranulomas (JXGs) are uncommon, benign diseases that are part of a larger category of non-Langerhans cell histiocytoses. They typically show up as one or more red or yellowish lumps, often found on the head or neck. Most JXGs develop either at birth or within the first year of life. While it's unusual, sometimes they can affect areas beyond the skin, with eye involvement being something to watch for according to existing literature. Generally, JXGs on the skin go away on their own and typically don't need treatment.
O manu'a mata e fa'aalia i le 10% o tagata e maua i le JXG ma e ono a'afia ai la latou va'ai. E ui lava e masani ona mou atu fa'afuase'i manu'a o le mata, e seasea fa'afuase'i ona fa'aleleia ma mana'omia togafitiga.